Alternative splicing and nonsense-mediated mRNA decay regulate mammalian ribosomal gene expression

Messenger RNAs containing premature stop codons are generally targeted for degradation through nonsense-mediated mRNA decay (NMD). This mechanism degrades aberrant transcripts derived from mutant genes containing nonsense or frameshift mutations. Wild-type genes also give rise to transcripts targete...

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Detalles Bibliográficos
Autores principales: Cuccurese, Monica, Russo, Giulia, Russo, Annapina, Pietropaolo, Concetta
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1270949/
https://www.ncbi.nlm.nih.gov/pubmed/16254077
http://dx.doi.org/10.1093/nar/gki905

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