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Cleavage of dsRNAs hyper-edited by ADARs occurs at preferred editing sites
Long double-stranded RNAs (dsRNAs) may undergo covalent modification (hyper-editing) by adenosine deaminases that act on RNA (ADARs), whereby up to 50–60% of adenosine residues are converted to inosine. Previously, we have described a ribonuclease activity in various cell extracts that specifically...
Autores principales: | Scadden, A. D. J., O'Connell, M. A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1270950/ https://www.ncbi.nlm.nih.gov/pubmed/16254076 http://dx.doi.org/10.1093/nar/gki909 |
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