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Metagenomics for studying unculturable microorganisms: cutting the Gordian knot
More than 99% of prokaryotes in the environment cannot be cultured in the laboratory, a phenomenon that limits our understanding of microbial physiology, genetics, and community ecology. One way around this problem is metagenomics, the culture-independent cloning and analysis of microbial DNA extrac...
Autores principales: | Schloss, Patrick D, Handelsman, Jo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1273625/ https://www.ncbi.nlm.nih.gov/pubmed/16086859 http://dx.doi.org/10.1186/gb-2005-6-8-229 |
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