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Ultrasensitization: Switch-Like Regulation of Cellular Signaling by Transcriptional Induction
Cellular signaling networks are subject to transcriptional and proteolytic regulation under both physiological and pathological conditions. For example, the expression of proteins subject to covalent modification by phosphorylation is known to be altered upon cellular differentiation or during carci...
Autores principales: | Legewie, Stefan, Blüthgen, Nils, Schäfer, Reinhold, Herzel, Hanspeter |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1274294/ https://www.ncbi.nlm.nih.gov/pubmed/16261195 http://dx.doi.org/10.1371/journal.pcbi.0010054 |
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