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Hydrophilic and lipophilic radiopharmaceuticals as tracers in pharmaceutical development: In vitro – In vivo studies
BACKGROUND: Scintigraphic studies have been performed to assess the release, both in vitro and in vivo, of radiotracers from tablet formulations. Four different tracers with differing physicochemical characteristics have been evaluated to assess their suitability as models for drug delivery. METHODS...
Autores principales: | Terán, Mariella, Savio, Eduardo, Paolino, Andrea, Frier, Malcolm |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1274329/ https://www.ncbi.nlm.nih.gov/pubmed/16232323 http://dx.doi.org/10.1186/1471-2385-5-5 |
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