Early correlation of microglial activation with enhanced tumor necrosis factor-alpha and monocyte chemoattractant protein-1 expression specifically within the entorhinal cortex of triple transgenic Alzheimer's disease mice

BACKGROUND: Alzheimer's disease is a complex neurodegenerative disorder characterized pathologically by a temporal and spatial progression of beta-amyloid (Aβ) deposition, neurofibrillary tangle formation, and synaptic degeneration. Inflammatory processes have been implicated in initiating and/...

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Detalles Bibliográficos
Autores principales: Janelsins, Michelle C, Mastrangelo, Michael A, Oddo, Salvatore, LaFerla, Frank M, Federoff, Howard J, Bowers, William J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1276812/
https://www.ncbi.nlm.nih.gov/pubmed/16232318
http://dx.doi.org/10.1186/1742-2094-2-23

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