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A trial of somatic gene targeting in vivo with an adenovirus vector
BACKGROUND: Gene targeting in vivo provides a potentially powerful method for gene analysis and gene therapy. In order to sensitively detect and accurately measure designed sequence changes, we have used a transgenic mouse system, MutaMouse, which has been developed for detection of mutation in vivo...
Autores principales: | Ino, Asami, Naito, Yasuhiro, Mizuguchi, Hiroyuki, Handa, Naofumi, Hayakawa, Takao, Kobayashi, Ichizo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1277836/ https://www.ncbi.nlm.nih.gov/pubmed/16219108 http://dx.doi.org/10.1186/1479-0556-3-8 |
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