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Contribution of the C-terminal tri-lysine regions of human immunodeficiency virus type 1 integrase for efficient reverse transcription and viral DNA nuclear import
BACKGROUND: In addition to mediating the integration process, HIV-1 integrase (IN) has also been implicated in different steps during viral life cycle including reverse transcription and viral DNA nuclear import. Although the karyophilic property of HIV-1 IN has been well demonstrated using a variet...
Autores principales: | Ao, Zhujun, Fowke, Keith R, Cohen, Éric A, Yao, Xiaojian |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1277849/ https://www.ncbi.nlm.nih.gov/pubmed/16232319 http://dx.doi.org/10.1186/1742-4690-2-62 |
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