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Assay for high glucose-mediated islet cell sensitization to apoptosis induced by streptozotocin and cytokines

Pancreatic β-cell apoptosis is known to participate in the β-cell destruction process that occurs in diabetes. It has been described that high glucose level induces a hyperfunctional status which could provoke apoptosis. This phenomenon is known as glucotoxicity and has been proposed that it can pla...

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Detalles Bibliográficos
Autores principales: Mellado-Gil, Jose M., Aguilar-Diosdado, Manuel
Formato: Texto
Lenguaje:English
Publicado: Biological Procedures Online 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1280327/
https://www.ncbi.nlm.nih.gov/pubmed/16281079
http://dx.doi.org/10.1251/bpo113