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Fetal Environment and Schizophrenia
Schizophrenia and related disorders are adult-onset illnesses with no definitively established risk factors. Several studies report that exposures to infection and nutritional deprivation during early development may elevate the risk of later developing schizophrenia, specifically during the prenata...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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National Institute of Environmental Health Sciences
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1280409/ https://www.ncbi.nlm.nih.gov/pubmed/16140635 http://dx.doi.org/10.1289/ehp.7572 |
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author | Opler, Mark G. A. Susser, Ezra S. |
author_facet | Opler, Mark G. A. Susser, Ezra S. |
author_sort | Opler, Mark G. A. |
collection | PubMed |
description | Schizophrenia and related disorders are adult-onset illnesses with no definitively established risk factors. Several studies report that exposures to infection and nutritional deprivation during early development may elevate the risk of later developing schizophrenia, specifically during the prenatal period. Preliminary evidence implicates lead exposure as well, suggesting that chemical exposures during early development may constitute a new class of risk factors for schizophrenia that has not been adequately investigated. Exposure to lead is given as an example of a chemical agent for which some effects have been described throughout the life course on both general neurodevelopmental outcomes and now on a specific psychiatric diagnosis. Findings from prospectively collected birth cohorts are offered as examples of both innovations in methodology and opportunities for future generations of investigators. |
format | Text |
id | pubmed-1280409 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2005 |
publisher | National Institute of Environmental Health Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-12804092005-11-30 Fetal Environment and Schizophrenia Opler, Mark G. A. Susser, Ezra S. Environ Health Perspect Research Schizophrenia and related disorders are adult-onset illnesses with no definitively established risk factors. Several studies report that exposures to infection and nutritional deprivation during early development may elevate the risk of later developing schizophrenia, specifically during the prenatal period. Preliminary evidence implicates lead exposure as well, suggesting that chemical exposures during early development may constitute a new class of risk factors for schizophrenia that has not been adequately investigated. Exposure to lead is given as an example of a chemical agent for which some effects have been described throughout the life course on both general neurodevelopmental outcomes and now on a specific psychiatric diagnosis. Findings from prospectively collected birth cohorts are offered as examples of both innovations in methodology and opportunities for future generations of investigators. National Institute of Environmental Health Sciences 2005-09 2005-05-26 /pmc/articles/PMC1280409/ /pubmed/16140635 http://dx.doi.org/10.1289/ehp.7572 Text en http://creativecommons.org/publicdomain/mark/1.0/ Publication of EHP lies in the public domain and is therefore without copyright. All text from EHP may be reprinted freely. Use of materials published in EHP should be acknowledged (for example, ?Reproduced with permission from Environmental Health Perspectives?); pertinent reference information should be provided for the article from which the material was reproduced. Articles from EHP, especially the News section, may contain photographs or illustrations copyrighted by other commercial organizations or individuals that may not be used without obtaining prior approval from the holder of the copyright. |
spellingShingle | Research Opler, Mark G. A. Susser, Ezra S. Fetal Environment and Schizophrenia |
title | Fetal Environment and Schizophrenia |
title_full | Fetal Environment and Schizophrenia |
title_fullStr | Fetal Environment and Schizophrenia |
title_full_unstemmed | Fetal Environment and Schizophrenia |
title_short | Fetal Environment and Schizophrenia |
title_sort | fetal environment and schizophrenia |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1280409/ https://www.ncbi.nlm.nih.gov/pubmed/16140635 http://dx.doi.org/10.1289/ehp.7572 |
work_keys_str_mv | AT oplermarkga fetalenvironmentandschizophrenia AT susserezras fetalenvironmentandschizophrenia |