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Systematic Discovery of New Recognition Peptides Mediating Protein Interaction Networks

Many aspects of cell signalling, trafficking, and targeting are governed by interactions between globular protein domains and short peptide segments. These domains often bind multiple peptides that share a common sequence pattern, or “linear motif” (e.g., SH3 binding to PxxP). Many domains are known...

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Detalles Bibliográficos
Autores principales: Neduva, Victor, Linding, Rune, Su-Angrand, Isabelle, Stark, Alexander, de Masi, Federico, Gibson, Toby J, Lewis, Joe, Serrano, Luis, Russell, Robert B
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1283537/
https://www.ncbi.nlm.nih.gov/pubmed/16279839
http://dx.doi.org/10.1371/journal.pbio.0030405