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The modeled structure of the RNA dependent RNA polymerase of GBV-C Virus suggests a role for motif E in Flaviviridae RNA polymerases

BACKGROUND: The Flaviviridae virus family includes major human and animal pathogens. The RNA dependent RNA polymerase (RdRp) plays a central role in the replication process, and thus is a validated target for antiviral drugs. Despite the increasing structural and enzymatic characterization of viral...

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Detalles Bibliográficos
Autores principales:	Ferron, François, Bussetta, Cécile, Dutartre, Hélène, Canard, Bruno
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1283970/ https://www.ncbi.nlm.nih.gov/pubmed/16225688 http://dx.doi.org/10.1186/1471-2105-6-255

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