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Disruption of Toxoplasma gondii Parasitophorous Vacuoles by the Mouse p47-Resistance GTPases

The p47 GTPases are essential for interferon-γ-induced cell-autonomous immunity against the protozoan parasite, Toxoplasma gondii, in mice, but the mechanism of resistance is poorly understood. We show that the p47 GTPases, including IIGP1, accumulate at vacuoles containing T. gondii. The accumulati...

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Detalles Bibliográficos
Autores principales:	Martens, Sascha, Parvanova, Iana, Zerrahn, Jens, Griffiths, Gareth, Schell, Gudrun, Reichmann, Gaby, Howard, Jonathan C
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2005
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1287907/ https://www.ncbi.nlm.nih.gov/pubmed/16304607 http://dx.doi.org/10.1371/journal.ppat.0010024

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