Increased Life Span due to Calorie Restriction in Respiratory-Deficient Yeast

A model for replicative life span extension by calorie restriction (CR) in yeast has been proposed whereby reduced glucose in the growth medium leads to activation of the NAD(+)–dependent histone deacetylase Sir2. One mechanism proposed for this putative activation of Sir2 is that CR enhances the ra...

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Detalles Bibliográficos
Autores principales: Kaeberlein, Matt, Hu, Di, Kerr, Emily O, Tsuchiya, Mitsuhiro, Westman, Eric A, Dang, Nick, Fields, Stanley, Kennedy, Brian K
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1287956/
https://www.ncbi.nlm.nih.gov/pubmed/16311627
http://dx.doi.org/10.1371/journal.pgen.0010069

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