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Construction and high cytoplasmic expression of a tumoricidal single-chain antibody against hepatocellular carcinoma

BACKGROUND: Hep27 monoclonal (Hep27 Mab) is an antibody against hepatocellular carcinoma. Hep27 Mab itself can inhibit the growth of a hepatocellular carcinoma cell line (HCC-S102). We attempted to produce a single-chain fragment (scFv), a small fragment containing an antigen-binding site of Hep27 M...

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Detalles Bibliográficos
Autores principales:	Sandee, Duanpen, Tungpradabkul, Sumalee, Tsukio, Manae, Imanaka, Tadayuki, Takagi, Masahiro
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2002
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC128817/ https://www.ncbi.nlm.nih.gov/pubmed/12227831 http://dx.doi.org/10.1186/1472-6750-2-16

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