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Specificity of DNA triple helix formation analyzed by a FRET assay

BACKGROUND: A third DNA strand can bind into the major groove of a homopurine duplex DNA to form a DNA triple helix. Sequence specific triplex formation can be applied for gene targeting, gene silencing and mutagenesis. RESULTS: We have analyzed triplex formation of two polypurine triplex forming ol...

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Detalles Bibliográficos
Autores principales: Reither, Sabine, Jeltsch, Albert
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC128820/
https://www.ncbi.nlm.nih.gov/pubmed/12323077
http://dx.doi.org/10.1186/1471-2091-3-27