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Specificity of DNA triple helix formation analyzed by a FRET assay
BACKGROUND: A third DNA strand can bind into the major groove of a homopurine duplex DNA to form a DNA triple helix. Sequence specific triplex formation can be applied for gene targeting, gene silencing and mutagenesis. RESULTS: We have analyzed triplex formation of two polypurine triplex forming ol...
Autores principales: | Reither, Sabine, Jeltsch, Albert |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC128820/ https://www.ncbi.nlm.nih.gov/pubmed/12323077 http://dx.doi.org/10.1186/1471-2091-3-27 |
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