Lessons learned from gene transfer approaches

Recent technological advances allow the transfer of genes to the synovial lining of joints. As well as opening novel opportunities for therapy, these techniques provide valuable new tools for the study of synovitis and other aspects of the biology of joints in health and disease. This article review...

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Detalles Bibliográficos
Autores principales: Evans, Christopher H, Ghivizzani, Steven C, Lechman, Eric R, Mi, Zhebao, Jaffurs, Daniel, Robbins, Paul D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 1999
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC128865/
https://www.ncbi.nlm.nih.gov/pubmed/11094409
http://dx.doi.org/10.1186/ar6
Descripción
Sumario:Recent technological advances allow the transfer of genes to the synovial lining of joints. As well as opening novel opportunities for therapy, these techniques provide valuable new tools for the study of synovitis and other aspects of the biology of joints in health and disease. This article reviews briefly the results of experiments in which selected genes have been transferred to the knee joints of healthy rabbits and rabbits with antigen-induced arthritis.

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