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The molecular mechanism of osteoclastogenesis in rheumatoid arthritis

Bone-resorbing osteoclasts are formed from hemopoietic cells of the monocyte–macrophage lineage under the control of bone-forming osteoblasts. We have cloned an osteoblast-derived factor essential for osteoclastogenesis, the receptor activator of NF-κB ligand (RANKL). Synovial fibroblasts and activa...

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Detalles Bibliográficos
Autores principales:	Udagawa, Nobuyuki, Kotake, Shigeru, Kamatani, Naoyuki, Takahashi, Naoyuki, Suda, Tatsuo
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2002
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC128939/ https://www.ncbi.nlm.nih.gov/pubmed/12223101

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