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Comparative Signature-Tagged Mutagenesis Identifies Pseudomonas Factors Conferring Resistance to the Pulmonary Collectin SP-A
The pulmonary collectin, surfactant protein A (SP-A), is a broad spectrum opsonin with microbicidal membrane permeabilization properties that plays a role in the innate immune response of the lung. However, the factors that govern SP-A's microbial specificity and the mechanisms by which it medi...
Autores principales: | Zhang, Shiping, Chen, Yi, Potvin, Eric, Sanschagrin, Francois, Levesque, Roger C, McCormack, Francis X, Lau, Gee W |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1291351/ https://www.ncbi.nlm.nih.gov/pubmed/16322768 http://dx.doi.org/10.1371/journal.ppat.0010031 |
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