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Xenopus frizzled-4S, a splicing variant of Xfz4 is a context-dependent activator and inhibitor of Wnt/β-catenin signaling
BACKGROUND: Secreted Frizzled related proteins (SFRPs) are extracellular regulators of Wnt signaling. These proteins contain an N-terminal cysteine rich domain (CRD) highly similar to the CRDs of the Frizzled family of seven-transmembrane proteins that act as Wnt receptors. SFRPs can bind to Wnts an...
Autores principales: | Swain, Rajeeb Kumar, Katoh, Masaru, Medina, Araceli, Steinbeisser, Herbert |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1291380/ https://www.ncbi.nlm.nih.gov/pubmed/16236168 http://dx.doi.org/10.1186/1478-811X-3-12 |
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