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The crucial role of particle surface reactivity in respirable quartz-induced reactive oxygen/nitrogen species formation and APE/Ref-1 induction in rat lung

Persistent inflammation and associated excessive oxidative stress have been crucially implicated in quartz-induced pulmonary diseases, including fibrosis and cancer. We have investigated the significance of the particle surface reactivity of respirable quartz dust in relation to the in vivo generati...

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Detalles Bibliográficos
Autores principales: Albrecht, Catrin, Knaapen, Ad M, Becker, Andrea, Höhr, Doris, Haberzettl, Petra, van Schooten, Frederik J, Borm, Paul JA, Schins, Roel PF
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1291407/
https://www.ncbi.nlm.nih.gov/pubmed/16266428
http://dx.doi.org/10.1186/1465-9921-6-129

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