Cargando…
The crucial role of particle surface reactivity in respirable quartz-induced reactive oxygen/nitrogen species formation and APE/Ref-1 induction in rat lung
Persistent inflammation and associated excessive oxidative stress have been crucially implicated in quartz-induced pulmonary diseases, including fibrosis and cancer. We have investigated the significance of the particle surface reactivity of respirable quartz dust in relation to the in vivo generati...
Autores principales: | Albrecht, Catrin, Knaapen, Ad M, Becker, Andrea, Höhr, Doris, Haberzettl, Petra, van Schooten, Frederik J, Borm, Paul JA, Schins, Roel PF |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1291407/ https://www.ncbi.nlm.nih.gov/pubmed/16266428 http://dx.doi.org/10.1186/1465-9921-6-129 |
Ejemplares similares
-
NF-κB dependent and independent mechanisms of quartz-induced proinflammatory activation of lung epithelial cells
por: van Berlo, Damien, et al.
Publicado: (2010) -
Contrasting macrophage activation by fine and ultrafine titanium dioxide particles is associated with different uptake mechanisms
por: Scherbart, Agnes M, et al.
Publicado: (2011) -
Activation of APE1/Ref-1 is dependent on reactive oxygen species generated after purinergic receptor stimulation by ATP
por: Pines, Alex, et al.
Publicado: (2005) -
Neutrophils amplify the formation of DNA adducts by benzo[a]pyrene in lung target cells.
por: Borm, P J, et al.
Publicado: (1997) -
Editor's Note to ‘Activation of APE1/Ref-1 is dependent on reactive oxygen species generated after purinergic receptor stimulation by ATP’
Publicado: (2022)