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Copper chelation with tetrathiomolybdate suppresses adjuvant-induced arthritis and inflammation-associated cachexia in rats
Tetrathiomolybdate (TM), a drug developed for Wilson's disease, produces an anti-angiogenic and anti-inflammatory effect by reducing systemic copper levels. TM therapy has proved effective in inhibiting the growth of tumors in animal tumor models and in cancer patients. We have hypothesized tha...
Autores principales: | Omoto, Atsushi, Kawahito, Yutaka, Prudovsky, Igor, Tubouchi, Yasunori, Kimura, Mizuho, Ishino, Hidetaka, Wada, Makoto, Yoshida, Makie, Kohno, Masataka, Yoshimura, Rikio, Yoshikawa, Toshikazu, Sano, Hajime |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1297562/ https://www.ncbi.nlm.nih.gov/pubmed/16277669 http://dx.doi.org/10.1186/ar1801 |
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