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Close encounters between active genes in the nucleus

A recent paper demonstrates that coregulated genes on different chromosomes show surprisingly high frequencies of colocalization within the nucleus; this complements similar results found previously for genes localized tens of megabases apart on a single chromosome. Colocalization could be related t...

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Detalles Bibliográficos
Autores principales: Chuang, Chien-Hui, Belmont, Andrew S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1297641/
https://www.ncbi.nlm.nih.gov/pubmed/16277755
http://dx.doi.org/10.1186/gb-2005-6-11-237
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author Chuang, Chien-Hui
Belmont, Andrew S
author_facet Chuang, Chien-Hui
Belmont, Andrew S
author_sort Chuang, Chien-Hui
collection PubMed
description A recent paper demonstrates that coregulated genes on different chromosomes show surprisingly high frequencies of colocalization within the nucleus; this complements similar results found previously for genes localized tens of megabases apart on a single chromosome. Colocalization could be related to the earlier observation of active genes associating with foci where RNA polymerase II is concentrated.
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spelling pubmed-12976412005-12-01 Close encounters between active genes in the nucleus Chuang, Chien-Hui Belmont, Andrew S Genome Biol Minireview A recent paper demonstrates that coregulated genes on different chromosomes show surprisingly high frequencies of colocalization within the nucleus; this complements similar results found previously for genes localized tens of megabases apart on a single chromosome. Colocalization could be related to the earlier observation of active genes associating with foci where RNA polymerase II is concentrated. BioMed Central 2005 2005-10-19 /pmc/articles/PMC1297641/ /pubmed/16277755 http://dx.doi.org/10.1186/gb-2005-6-11-237 Text en Copyright © 2005 BioMed Central Ltd
spellingShingle Minireview
Chuang, Chien-Hui
Belmont, Andrew S
Close encounters between active genes in the nucleus
title Close encounters between active genes in the nucleus
title_full Close encounters between active genes in the nucleus
title_fullStr Close encounters between active genes in the nucleus
title_full_unstemmed Close encounters between active genes in the nucleus
title_short Close encounters between active genes in the nucleus
title_sort close encounters between active genes in the nucleus
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1297641/
https://www.ncbi.nlm.nih.gov/pubmed/16277755
http://dx.doi.org/10.1186/gb-2005-6-11-237
work_keys_str_mv AT chuangchienhui closeencountersbetweenactivegenesinthenucleus
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