The neuroblast and angioblast chemotaxic factor SDF-1 (CXCL12) expression is briefly up regulated by reactive astrocytes in brain following neonatal hypoxic-ischemic injury

BACKGROUND: Stromal cell-derived factor 1 (SDF-1 or CXCL12) is chemotaxic for CXCR4 expressing bone marrow-derived cells. It functions in brain embryonic development and in response to ischemic injury in helping guide neuroblast migration and vasculogenesis. In experimental adult stroke models SDF-1...

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Detalles Bibliográficos
Autores principales: Miller, Jason T, Bartley, John H, Wimborne, Hereward JC, Walker, Aisha L, Hess, David C, Hill, William D, Carroll, James E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1298306/
https://www.ncbi.nlm.nih.gov/pubmed/16259636
http://dx.doi.org/10.1186/1471-2202-6-63

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