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A second look at cellular mRNA sequences said to function as internal ribosome entry sites

This review takes a second look at a set of mRNAs that purportedly employ an alternative mechanism of initiation when cap-dependent translation is reduced during mitosis or stress conditions. A closer look is necessary because evidence cited in support of the internal initiation hypothesis is often...

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Detalles Bibliográficos
Autor principal: Kozak, Marilyn
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1298923/
https://www.ncbi.nlm.nih.gov/pubmed/16314320
http://dx.doi.org/10.1093/nar/gki958