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EGF Receptor-Targeted Synthetic Double-Stranded RNA Eliminates Glioblastoma, Breast Cancer, and Adenocarcinoma Tumors in Mice

BACKGROUND: Glioblastoma multiforme (GBM) is the most lethal form of brain cancer. With the available treatments, survival does not exceed 12–14 mo from the time of diagnosis. We describe a novel strategy to selectively induce the death of glioblastoma cells and other cancer cells that over-express...

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Detalles Bibliográficos
Autores principales:	Shir, Alexei, Ogris, Manfred, Wagner, Ernst, Levitzki, Alexander
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2006
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1298941/ https://www.ncbi.nlm.nih.gov/pubmed/16318410 http://dx.doi.org/10.1371/journal.pmed.0030006

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