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Association of MHC and rheumatoid arthritis: Regulatory role of HLA class II molecules in animal models of RA - studies on transgenic/knockout mice
Human leucocyte antigen (HLA) class II molecules have been shown to be associated with predisposition to rheumatoid arthritis (RA). We generated HLA-DR and DQ transgenic mice that lacked endogenous class II molecules to study the interaction between the DR and DQ molecules and define the immunologic...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2000
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC130003/ https://www.ncbi.nlm.nih.gov/pubmed/11094430 http://dx.doi.org/10.1186/ar88 |