What you should know about PR3-ANCA: Conformational requirements of proteinase 3 (PR3) for enzymatic activity and recognition by PR3-ANCA

The neutrophil azurophil granule constituent proteinase 3 (PR3) is the principal antigen for anti-neutrophil cytoplasmic antibodies (ANCA) in Wegener's granulomatosis. The conformation of the mature PR3 enzyme results from intracellular post-translational processing. The nascent molecule underg...

Descripción completa

Detalles Bibliográficos
Autor principal: Specks, Ulrich
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2000
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC130016/
https://www.ncbi.nlm.nih.gov/pubmed/11094439
http://dx.doi.org/10.1186/ar99

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC130016/
https://www.ncbi.nlm.nih.gov/pubmed/11094439
http://dx.doi.org/10.1186/ar99

Ejemplares similares