The PEST sequence does not contribute to the stability of the cystic fibrosis transmembrane conductance regulator

BACKGROUND: Endoplasmic reticulum retention of misfolded cystic fibrosis transmembrane conductance regulator (CFTR) mutants and their rapid degradation is the major cause of cystic fibrosis (CF). An important goal is to understand the mechanism of how the misfolded proteins are recognized, retained,...

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Detalles Bibliográficos
Autores principales: Chen, Eva Y, Clarke, David M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC130031/
https://www.ncbi.nlm.nih.gov/pubmed/12361483
http://dx.doi.org/10.1186/1471-2091-3-29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC130031/
https://www.ncbi.nlm.nih.gov/pubmed/12361483
http://dx.doi.org/10.1186/1471-2091-3-29

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