Cargando…
The PEST sequence does not contribute to the stability of the cystic fibrosis transmembrane conductance regulator
BACKGROUND: Endoplasmic reticulum retention of misfolded cystic fibrosis transmembrane conductance regulator (CFTR) mutants and their rapid degradation is the major cause of cystic fibrosis (CF). An important goal is to understand the mechanism of how the misfolded proteins are recognized, retained,...
| Autores principales: | , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2002
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC130031/ https://www.ncbi.nlm.nih.gov/pubmed/12361483 http://dx.doi.org/10.1186/1471-2091-3-29 |