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In vitro correction of cystic fibrosis epithelial cell lines by small fragment homologous replacement (SFHR) technique
BACKGROUND: SFHR (small fragment homologous replacement)-mediated targeting is a process that has been used to correct specific mutations in mammalian cells. This process involves both chemical and cellular factors that are not yet defined. To evaluate potential of this technique for gene therapy it...
Autores principales: | Sangiuolo, Federica, Bruscia, Emanuela, Serafino, Annalucia, Nardone, Anna Maria, Bonifazi, Emanuela, Lais, Monica, Gruenert, Dieter C, Novelli, Giuseppe |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC130050/ https://www.ncbi.nlm.nih.gov/pubmed/12243649 http://dx.doi.org/10.1186/1471-2350-3-8 |
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