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In vitro correction of cystic fibrosis epithelial cell lines by small fragment homologous replacement (SFHR) technique

BACKGROUND: SFHR (small fragment homologous replacement)-mediated targeting is a process that has been used to correct specific mutations in mammalian cells. This process involves both chemical and cellular factors that are not yet defined. To evaluate potential of this technique for gene therapy it...

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Detalles Bibliográficos
Autores principales: Sangiuolo, Federica, Bruscia, Emanuela, Serafino, Annalucia, Nardone, Anna Maria, Bonifazi, Emanuela, Lais, Monica, Gruenert, Dieter C, Novelli, Giuseppe
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC130050/
https://www.ncbi.nlm.nih.gov/pubmed/12243649
http://dx.doi.org/10.1186/1471-2350-3-8

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