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CTCF binds the proximal exonic region of hTERT and inhibits its transcription
The expression of the catalytic subunit (hTERT) represents the limiting factor for telomerase activity. Previously, we detected a transcriptional repressor effect of the proximal exonic region (first two exons) of the hTERT gene. To better understand the mechanism involved and to identify a potentia...
Autores principales: | Renaud, Stéphanie, Loukinov, Dmitri, Bosman, Fred T., Lobanenkov, Victor, Benhattar, Jean |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1301598/ https://www.ncbi.nlm.nih.gov/pubmed/16326864 http://dx.doi.org/10.1093/nar/gki989 |
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