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Interleukin-4 (IL4) and Interleukin-4 receptor (IL4RA) polymorphisms in asthma: a case control study

BACKGROUND: IL4/IL4RA pathway plays an important role in atopy and asthma. Different polymorphisms in IL4 and IL4RA genes have been described. Particularly, -33C>TIL4 and 576Q>RIL4RA SNPs have been independently associated to atopy and asthma. The purpose of this study was to analyse these pol...

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Detalles Bibliográficos
Autores principales: Isidoro-García, María, Dávila, Ignacio, Laffond, Elena, Moreno, Esther, Lorente, Félix, González-Sarmiento, Rogelio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1310519/
https://www.ncbi.nlm.nih.gov/pubmed/16313681
http://dx.doi.org/10.1186/1476-7961-3-15