Cargando…

Organotins Disrupt the 11β-Hydroxysteroid Dehydrogenase Type 2–Dependent Local Inactivation of Glucocorticoids

Organotins, important environmental pollutants widely used in agricultural and industrial applications, accumulate in the food chain and induce imposex in several marine species as well as neurotoxic and immunotoxic effects in higher animals. Reduced birth weight and thymus involution, observed upon...

Descripción completa

Detalles Bibliográficos
Autores principales:	Atanasov, Atanas G., Nashev, Lyubomir G., Tam, Steven, Baker, Michael E., Odermatt, Alex
Formato:	Texto
Lenguaje:	English
Publicado:	National Institute of Environmental Health Sciences 2005
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1310925/ https://www.ncbi.nlm.nih.gov/pubmed/16263518 http://dx.doi.org/10.1289/ehp.8209

Ejemplares similares

Cysteine-10 on 17β-Hydroxysteroid Dehydrogenase 1 Has Stabilizing Interactions in the Cofactor Binding Region and Renders Sensitivity to Sulfhydryl Modifying Chemicals
por: Nashev, Lyubomir G., et al.
Publicado: (2013)

Hexose-6-phosphate Dehydrogenase Modulates 11β-Hydroxysteroid Dehydrogenase Type 1-Dependent Metabolism of 7-keto- and 7β-hydroxy-neurosteroids
por: Nashev, Lyubomir G., et al.
Publicado: (2007)

Mineralocorticoid and glucocorticoid receptors differentially regulate NF-kappaB activity and pro-inflammatory cytokine production in murine BV-2 microglial cells
por: Chantong, Boonrat, et al.
Publicado: (2012)

Central Glucocorticoid Administration Promotes Weight Gain and Increased 11β-Hydroxysteroid Dehydrogenase Type 1 Expression in White Adipose Tissue
por: Veyrat-Durebex, Christelle, et al.
Publicado: (2012)

Changes in 11β-Hydroxysteroid Dehydrogenase and Glucocorticoid Receptor Expression in Kawasaki Disease
por: Wang, Juanli, et al.
Publicado: (2017)

Posaconazole-Induced Hypertension Due to Inhibition of 11β-Hydroxylase and 11β-Hydroxysteroid Dehydrogenase 2
por: Thompson, George R, et al.
Publicado: (2019)

Potential Antiosteoporotic Natural Product Lead Compounds That Inhibit 17β-Hydroxysteroid Dehydrogenase Type 2
por: Vuorinen, Anna, et al.
Publicado: (2017)

Virtual Screening as a Strategy for the Identification of Xenobiotics Disrupting Corticosteroid Action
por: Nashev, Lyubomir G., et al.
Publicado: (2012)

Changing glucocorticoid action: 11β-Hydroxysteroid dehydrogenase type 1 in acute and chronic inflammation
por: Chapman, Karen E., et al.
Publicado: (2013)

11β-Hydroxysteroid Dehydrogenase Type 1 Regulates Glucocorticoid-Induced Insulin Resistance in Skeletal Muscle
por: Morgan, Stuart A., et al.
Publicado: (2009)

11β-Hydroxysteroid Dehydrogenase 2 in Preeclampsia
por: Kosicka, Katarzyna, et al.
Publicado: (2016)

11β-Hydroxysteroid dehydrogenases control access of 7β,27-dihydroxycholesterol to retinoid-related orphan receptor γ
por: Beck, Katharina R., et al.
Publicado: (2019)

Characterisation of the cancer-associated glucocorticoid system: key role of 11β-hydroxysteroid dehydrogenase type 2
por: Cirillo, Nicola, et al.
Publicado: (2017)

The ratio of ursodeoxycholyltaurine to 7‐oxolithocholyltaurine serves as a biomarker of decreased 11β‐hydroxysteroid dehydrogenase 1 activity in mouse
por: Weingartner, Michael, et al.
Publicado: (2021)

Effect of Glucocorticoid and 11β-Hydroxysteroid-Dehydrogenase Type 1 (11β-HSD1) in Neurological and Psychiatric Disorders
por: Dodd, Seetal, et al.
Publicado: (2022)

11β-Hydroxysteroid dehydrogenase-1 is involved in bile acid homeostasis by modulating fatty acid transport protein-5 in the liver of mice()
por: Penno, Carlos A., et al.
Publicado: (2014)

11β-Hydroxysteroid Dehydrogenase Type 1 Inhibition Attenuates the Adverse Effects of Glucocorticoids on Dermal Papilla Cells
por: Lee, Sang Eun, et al.
Publicado: (2017)

11β-Hydroxysteroid Dehydrogenases and Hypertension in the Metabolic Syndrome
por: Bailey, Matthew A.
Publicado: (2017)

Pharmacophore Models and Pharmacophore-Based Virtual Screening: Concepts and Applications Exemplified on Hydroxysteroid Dehydrogenases
por: Kaserer, Teresa, et al.
Publicado: (2015)

Interference of Paraben Compounds with Estrogen Metabolism by Inhibition of 17β-Hydroxysteroid Dehydrogenases
por: Engeli, Roger T., et al.
Publicado: (2017)

The increased ratio of 11β-hydroxysteroid dehydrogenase type 1 versus 11β-hydroxysteroid dehydrogenase type 2 in chronic periodontitis irrespective of obesity
por: Nakata, Takaya, et al.
Publicado: (2016)

Lack of Significant Metabolic Abnormalities in Mice with Liver-Specific Disruption of 11β-Hydroxysteroid Dehydrogenase Type 1
por: Lavery, Gareth G., et al.
Publicado: (2012)

Alteration of 11β-Hydroxysteroid Dehydrogenase Type 1 and Glucocorticoid Receptor by Ethanol in Rat Liver and Mouse Hepatoma Cells
por: Meng, Zhaojie, et al.
Publicado: (2013)

Idiopathic intracranial hypertension, hormones, and 11β-hydroxysteroid dehydrogenases
por: Markey, Keira A, et al.
Publicado: (2016)

Cortisol, Hypertension and Obesity: The Role of 11β-Hydroxysteroid Dehydrogenase
por: Stewart, Paul M
Publicado: (1998)

The Effects of Piper Sarmentosum Water Extract on the Expression and Activity of 11β-Hydroxysteroid Dehydrogenase Type 1 in the Bones with Excessive Glucocorticoids
por: Suhana Mohd Ramli, Elvy, et al.
Publicado: (2012)

Effect of Luteolin on 11Beta-Hydroxysteroid Dehydrogenase in Rat Liver and Kidney
por: Tang, Lei, et al.
Publicado: (2015)

Diethylstilbestrol inhibits human and rat 11β-hydroxysteroid dehydrogenase 2
por: Wang, Yiyan, et al.
Publicado: (2019)

Glucocorticoid activation by 11β‐hydroxysteroid dehydrogenase enzymes in relation to inflammation and glycaemic control in chronic kidney disease: A cross‐sectional study
por: Sagmeister, Michael S., et al.
Publicado: (2018)

Role of 11β-hydroxysteroid dehydrogenase type 1 in the development of atopic dermatitis
por: Lee, Noo Ri, et al.
Publicado: (2020)

Zebrafish 20β-Hydroxysteroid Dehydrogenase Type 2 Is Important for Glucocorticoid Catabolism in Stress Response
por: Tokarz, Janina, et al.
Publicado: (2013)

Ontogeny of adrenal-like glucocorticoid synthesis pathway and of 20α-hydroxysteroid dehydrogenase in the mouse lung
por: Boucher, Eric, et al.
Publicado: (2014)

Down-Regulation of 11β-Hydroxysteroid Dehydrogenase Type 2 by Bortezomib Sensitizes Jurkat Leukemia T Cells against Glucocorticoid-Induced Apoptosis
por: Tao, Yi, et al.
Publicado: (2013)

Piper sarmentosum Effects on 11β-Hydroxysteroid Dehydrogenase Type 1 Enzyme in Serum and Bone in Rat Model of Glucocorticoid-Induced Osteoporosis
por: Mohamad Asri, Siti Fadziyah, et al.
Publicado: (2016)

Ecdysteroids from the Korean Endemic Species Ajuga spectabilis with Activities against Glucocorticoid Receptors and 11β-Hydroxysteroid Dehydrogenase Type 1
por: Park, InWha, et al.
Publicado: (2023)

Dibutyltin Disrupts Glucocorticoid Receptor Function and Impairs Glucocorticoid-Induced Suppression of Cytokine Production
por: Gumy, Christel, et al.
Publicado: (2008)

Ligand-Based Pharmacophore Modeling and Virtual Screening for the Discovery of Novel 17β-Hydroxysteroid Dehydrogenase 2 Inhibitors
por: Vuorinen, Anna, et al.
Publicado: (2014)

Modulation of 11β-Hydroxysteroid Dehydrogenase as a Strategy to Reduce Vascular Inflammation
por: Hadoke, Patrick W. F., et al.
Publicado: (2013)

Effect of Eclipta prostrata on 11Beta-Hydroxysteroid Dehydrogenase in Rat Liver and Kidney
por: Xu, Chenshu, et al.
Publicado: (2014)

Zearalenone Inhibits Rat and Human 11β-Hydroxysteroid Dehydrogenase Type 2
por: Li, Linxi, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_3jssr4hrrui1qtht27inbukuav