Cargando…

Identification of genes involved in Ca(2+ )ionophore A23187-mediated apoptosis and demonstration of a high susceptibility for transcriptional repression of cell cycle genes in B lymphoblasts from a patient with Scott syndrome

BACKGROUND: In contrast to other agents able to induce apoptosis of cultured cells, Ca(2+ )ionophore A23187 was shown to elicit direct activation of intracellular signal(s). The phenotype of the cells derived from patients having the hemorrhagic disease Scott syndrome, is associated with an abnormal...

Descripción completa

Detalles Bibliográficos
Autores principales: Kozian, Detlef, Proulle, Valérie, Nitsche, Almut, Galitzine, Marie, Martinez, Marie-Carmen, Schumann, Beatrice, Meyer, Dominique, Herrmann, Matthias, Freyssinet, Jean-Marie, Kerbiriou-Nabias, Danièle
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1312317/
https://www.ncbi.nlm.nih.gov/pubmed/16242039
http://dx.doi.org/10.1186/1471-2164-6-146