Identification of genes involved in Ca(2+ )ionophore A23187-mediated apoptosis and demonstration of a high susceptibility for transcriptional repression of cell cycle genes in B lymphoblasts from a patient with Scott syndrome

BACKGROUND: In contrast to other agents able to induce apoptosis of cultured cells, Ca(2+ )ionophore A23187 was shown to elicit direct activation of intracellular signal(s). The phenotype of the cells derived from patients having the hemorrhagic disease Scott syndrome, is associated with an abnormal...

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Detalles Bibliográficos
Autores principales: Kozian, Detlef, Proulle, Valérie, Nitsche, Almut, Galitzine, Marie, Martinez, Marie-Carmen, Schumann, Beatrice, Meyer, Dominique, Herrmann, Matthias, Freyssinet, Jean-Marie, Kerbiriou-Nabias, Danièle
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1312317/
https://www.ncbi.nlm.nih.gov/pubmed/16242039
http://dx.doi.org/10.1186/1471-2164-6-146

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