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Quantum dots to monitor RNAi delivery and improve gene silencing
A critical issue in using RNA interference for identifying genotype/phenotype correlations is the uniformity of gene silencing within a cell population. Variations in transfection efficiency, delivery-induced cytotoxicity and ‘off target’ effects at high siRNA concentrations can confound the interpr...
Autores principales: | Chen, Alice A., Derfus, Austin M., Khetani, Salman R., Bhatia, Sangeeta N. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1312364/ https://www.ncbi.nlm.nih.gov/pubmed/16352864 http://dx.doi.org/10.1093/nar/gni188 |
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