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Endothelial Lipase Concentrations Are Increased in Metabolic Syndrome and Associated with Coronary Atherosclerosis

BACKGROUND: Endothelial lipase (EL), a new member of the lipase family, has been shown to modulate high-density lipoprotein (HDL-C) metabolism and atherosclerosis in mouse models. We hypothesized that EL concentrations would be associated with decreased HDL-C and increased atherosclerosis in humans....

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Detalles Bibliográficos
Autores principales: Badellino, Karen O, Wolfe, Megan L, Reilly, Muredach P, Rader, Daniel J
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1316064/
https://www.ncbi.nlm.nih.gov/pubmed/16354105
http://dx.doi.org/10.1371/journal.pmed.0030022