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Interleukin-1 Stimulates β-Cell Necrosis and Release of the Immunological Adjuvant HMGB1
BACKGROUND: There are at least two phases of β-cell death during the development of autoimmune diabetes: an initiation event that results in the release of β-cell-specific antigens, and a second, antigen-driven event in which β-cell death is mediated by the actions of T lymphocytes. In this report,...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1316065/ https://www.ncbi.nlm.nih.gov/pubmed/16354107 http://dx.doi.org/10.1371/journal.pmed.0030017 |