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DNA base flipping by a base pair-mimic nucleoside

On the basis of non-covalent bond interactions in nucleic acids, we synthesized the deoxyadenosine derivatives tethering a phenyl group (X) and a naphthyl group (Z) by an amide linker, which mimic a Watson–Crick base pair. Circular dichroism spectra indicated that the duplexes containing X and Z for...

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Detalles Bibliográficos
Autores principales: Nakano, Shu-ichi, Uotani, Yuuki, Uenishi, Kazuya, Fujii, Masayuki, Sugimoto, Naoki
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1316115/
https://www.ncbi.nlm.nih.gov/pubmed/16361269
http://dx.doi.org/10.1093/nar/gki1018