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Comparative levels and time trends in blood pressure, total cholesterol, Body Mass Index and smoking among Caucasian and South-Asian participants of a UK primary-care based cardiovascular risk factor screening programme
BACKGROUND: Individuals of South-Asian origin have a comparatively higher cardiovascular disease burden, but there is uncertainty about whether this is due to differences in risk factor levels and trends. We therefore studied comparative levels and time trends in blood pressure (BP), total cholester...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1316876/ https://www.ncbi.nlm.nih.gov/pubmed/16313671 http://dx.doi.org/10.1186/1471-2458-5-125 |
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author | Lyratzopoulos, Georgios McElduff, Patrick Heller, Richard F Hanily, Margaret Lewis, Philip S |
author_facet | Lyratzopoulos, Georgios McElduff, Patrick Heller, Richard F Hanily, Margaret Lewis, Philip S |
author_sort | Lyratzopoulos, Georgios |
collection | PubMed |
description | BACKGROUND: Individuals of South-Asian origin have a comparatively higher cardiovascular disease burden, but there is uncertainty about whether this is due to differences in risk factor levels and trends. We therefore studied comparative levels and time trends in blood pressure (BP), total cholesterol, body mass index (BMI) and current smoking among UK Caucasian and South-Asian individuals. METHODS: Repeatable cross-sectional survey of men and women aged 35–60 attending for first screening as part of a primary-care based cardiovascular risk factor screening programme 1989 and 1999. RESULTS: Of 34,122 men and 37,294 women participants, 499 men (1.5%)and 381 women (1%) were of South-Asian origin. South-Asian men had lower systolic [(-4.91 mmHg (95% Confidence Iterval (CI): -3.58 to -6.23)] and diastolic BP [-2.87 mmHg (-2.02 to -3.72)], with no significant differences in cholesterol and BMI. South-Asian women had lower systolic BP [-1.77 mmHg, 95% (-0.21 to -3.33)], diastolic BP [-1.87 mmHg (-0.92 to -2.82)], cholesterol [-0.24 mmol/l (-0.08 to -0.39)]; and higher BMI [+0.78 kg/m(2 )(0.25 to 1.3)]. South-Asian men and women had significantly lower prevalence of self-reported current smoking (29.0% and 1.8% respectively). With the exception of self-reported current smoking, between ethnic group risk factor trends were not converging. CONCLUSION: With the exception of women's BMI, South-Asian individuals had either lower or similar levels of the examined cardiovascular risk factors, compared with Caucasian individuals. Although time trends in smoking were converging, other risk factors trends were similar between the two ethnic groups. Overall the findings do not support the hypothesis that the relatively high cardiovascular disease burden in UK South-Asians is due to higher levels exposure to the examined risk factors. Other hypotheses, such as higher frequency of diabetes and increased genetic predisposition, require further exploration. |
format | Text |
id | pubmed-1316876 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2005 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-13168762006-11-24 Comparative levels and time trends in blood pressure, total cholesterol, Body Mass Index and smoking among Caucasian and South-Asian participants of a UK primary-care based cardiovascular risk factor screening programme Lyratzopoulos, Georgios McElduff, Patrick Heller, Richard F Hanily, Margaret Lewis, Philip S BMC Public Health Research Article BACKGROUND: Individuals of South-Asian origin have a comparatively higher cardiovascular disease burden, but there is uncertainty about whether this is due to differences in risk factor levels and trends. We therefore studied comparative levels and time trends in blood pressure (BP), total cholesterol, body mass index (BMI) and current smoking among UK Caucasian and South-Asian individuals. METHODS: Repeatable cross-sectional survey of men and women aged 35–60 attending for first screening as part of a primary-care based cardiovascular risk factor screening programme 1989 and 1999. RESULTS: Of 34,122 men and 37,294 women participants, 499 men (1.5%)and 381 women (1%) were of South-Asian origin. South-Asian men had lower systolic [(-4.91 mmHg (95% Confidence Iterval (CI): -3.58 to -6.23)] and diastolic BP [-2.87 mmHg (-2.02 to -3.72)], with no significant differences in cholesterol and BMI. South-Asian women had lower systolic BP [-1.77 mmHg, 95% (-0.21 to -3.33)], diastolic BP [-1.87 mmHg (-0.92 to -2.82)], cholesterol [-0.24 mmol/l (-0.08 to -0.39)]; and higher BMI [+0.78 kg/m(2 )(0.25 to 1.3)]. South-Asian men and women had significantly lower prevalence of self-reported current smoking (29.0% and 1.8% respectively). With the exception of self-reported current smoking, between ethnic group risk factor trends were not converging. CONCLUSION: With the exception of women's BMI, South-Asian individuals had either lower or similar levels of the examined cardiovascular risk factors, compared with Caucasian individuals. Although time trends in smoking were converging, other risk factors trends were similar between the two ethnic groups. Overall the findings do not support the hypothesis that the relatively high cardiovascular disease burden in UK South-Asians is due to higher levels exposure to the examined risk factors. Other hypotheses, such as higher frequency of diabetes and increased genetic predisposition, require further exploration. BioMed Central 2005-11-28 /pmc/articles/PMC1316876/ /pubmed/16313671 http://dx.doi.org/10.1186/1471-2458-5-125 Text en Copyright © 2005 Lyratzopoulos et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Lyratzopoulos, Georgios McElduff, Patrick Heller, Richard F Hanily, Margaret Lewis, Philip S Comparative levels and time trends in blood pressure, total cholesterol, Body Mass Index and smoking among Caucasian and South-Asian participants of a UK primary-care based cardiovascular risk factor screening programme |
title | Comparative levels and time trends in blood pressure, total cholesterol, Body Mass Index and smoking among Caucasian and South-Asian participants of a UK primary-care based cardiovascular risk factor screening programme |
title_full | Comparative levels and time trends in blood pressure, total cholesterol, Body Mass Index and smoking among Caucasian and South-Asian participants of a UK primary-care based cardiovascular risk factor screening programme |
title_fullStr | Comparative levels and time trends in blood pressure, total cholesterol, Body Mass Index and smoking among Caucasian and South-Asian participants of a UK primary-care based cardiovascular risk factor screening programme |
title_full_unstemmed | Comparative levels and time trends in blood pressure, total cholesterol, Body Mass Index and smoking among Caucasian and South-Asian participants of a UK primary-care based cardiovascular risk factor screening programme |
title_short | Comparative levels and time trends in blood pressure, total cholesterol, Body Mass Index and smoking among Caucasian and South-Asian participants of a UK primary-care based cardiovascular risk factor screening programme |
title_sort | comparative levels and time trends in blood pressure, total cholesterol, body mass index and smoking among caucasian and south-asian participants of a uk primary-care based cardiovascular risk factor screening programme |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1316876/ https://www.ncbi.nlm.nih.gov/pubmed/16313671 http://dx.doi.org/10.1186/1471-2458-5-125 |
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