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Multiple sequence alignment accuracy and evolutionary distance estimation
BACKGROUND: Sequence alignment is a common tool in bioinformatics and comparative genomics. It is generally assumed that multiple sequence alignment yields better results than pair wise sequence alignment, but this assumption has rarely been tested, and never with the control provided by simulation...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1318491/ https://www.ncbi.nlm.nih.gov/pubmed/16305750 http://dx.doi.org/10.1186/1471-2105-6-278 |