Genetic mapping of putative Chrna7 and Luzp2 neuronal transcriptional enhancers due to impact of a transgene-insertion and 6.8 Mb deletion in a mouse model of Prader-Willi and Angelman syndromes

BACKGROUND: Prader-Willi and Angelman syndrome (PWS and AS) patients typically have an ~5 Mb deletion of human chromosome 15q11-q13, of opposite parental origin. A mouse model of PWS and AS has a transgenic insertion-deletion (TgPWS/TgAS) of chromosome 7B/C subsequent to paternal or maternal inherit...

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Detalles Bibliográficos
Autores principales: Stefan, Mihaela, Claiborn, Kathryn C, Stasiek, Edyta, Chai, Jing-Hua, Ohta, Tohru, Longnecker, Richard, Greally, John M, Nicholls, Robert D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1322230/
https://www.ncbi.nlm.nih.gov/pubmed/16280085
http://dx.doi.org/10.1186/1471-2164-6-157

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