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Hyperresponsiveness to inhaled but not intravenous methacholine during acute respiratory syncytial virus infection in mice
BACKGROUND: To characterise the acute physiological and inflammatory changes induced by low-dose RSV infection in mice. METHODS: BALB/c mice were infected as adults (8 wk) or weanlings (3 wk) with 1 × 10(5 )pfu of RSV A2 or vehicle (intranasal, 30 μl). Inflammation, cytokines and inflammatory marker...
Autores principales: | Collins, Rachel A, Gualano, Rosa C, Zosky, Graeme R, Atkins, Constance L, Turner, Debra J, Colasurdo, Giuseppe N, Sly, Peter D |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1325022/ https://www.ncbi.nlm.nih.gov/pubmed/16324223 http://dx.doi.org/10.1186/1465-9921-6-142 |
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