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XRCC1 is phosphorylated by DNA-dependent protein kinase in response to DNA damage

The two BRCT domains (BRCT1 and BRCT2) of XRCC1 mediate a network of protein–protein interactions with several key factors of the DNA single-strand breaks (SSBs) and base damage repair pathways. BRCT1 is required for the immediate poly(ADP–ribose)-dependent recruitment of XRCC1 to DNA breaks and is...

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Detalles Bibliográficos
Autores principales:	Lévy, Nicolas, Martz, Adeline, Bresson, Anne, Spenlehauer, Catherine, de Murcia, Gilbert, Ménissier-de Murcia, Josiane
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2006
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1325201/ https://www.ncbi.nlm.nih.gov/pubmed/16397295 http://dx.doi.org/10.1093/nar/gkj409

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