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Four-base codon mediated mRNA display to construct peptide libraries that contain multiple nonnatural amino acids
In vitro selection and directed evolution of peptides from mRNA display are powerful strategies to find novel peptide ligands that bind to target biomolecules. In this study, we expanded the mRNA display method to include multiple nonnatural amino acids by introducing three different four-base codon...
Autores principales: | Muranaka, Norihito, Hohsaka, Takahiro, Sisido, Masahiko |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1325208/ https://www.ncbi.nlm.nih.gov/pubmed/16397292 http://dx.doi.org/10.1093/nar/gnj003 |
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