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Repolarization of the action potential enabled by Na(+ )channel deactivation in PSpice simulation of cardiac muscle propagation

BACKGROUND: In previous studies on propagation of simulated action potentials (APs) in cardiac muscle using PSpice modeling, we reported that a second black-box (BB) could not be inserted into the K(+ )leg of the basic membrane unit because that caused the PSpice program to become very unstable. The...

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Detalles Bibliográficos
Autores principales: Ramasamy, Lakshminarayanan, Sperelakis, Nicholas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1326226/
https://www.ncbi.nlm.nih.gov/pubmed/16343352
http://dx.doi.org/10.1186/1742-4682-2-48