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Genome-wide identification of the regulatory targets of a transcription factor using biochemical characterization and computational genomic analysis

BACKGROUND: A major challenge in computational genomics is the development of methodologies that allow accurate genome-wide prediction of the regulatory targets of a transcription factor. We present a method for target identification that combines experimental characterization of binding requirement...

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Detalles Bibliográficos
Autores principales: Jolly, Emmitt R, Chin, Chen-Shan, Herskowitz, Ira, Li, Hao
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1326232/
https://www.ncbi.nlm.nih.gov/pubmed/16297241
http://dx.doi.org/10.1186/1471-2105-6-275