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Genome-wide identification of the regulatory targets of a transcription factor using biochemical characterization and computational genomic analysis
BACKGROUND: A major challenge in computational genomics is the development of methodologies that allow accurate genome-wide prediction of the regulatory targets of a transcription factor. We present a method for target identification that combines experimental characterization of binding requirement...
Autores principales: | Jolly, Emmitt R, Chin, Chen-Shan, Herskowitz, Ira, Li, Hao |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1326232/ https://www.ncbi.nlm.nih.gov/pubmed/16297241 http://dx.doi.org/10.1186/1471-2105-6-275 |
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